With over 1,000 clinical trials published in peer-reviewed journals, probiotics are among the most studied food supplements in the world. Here are the most solidly documented benefits.
Probiotics facilitate food breakdown, improve nutrient absorption, and prevent digestive disorders such as bloating, constipation, and diarrhea. They also relieve irritable bowel syndrome (IBS) and leaky gut.
A healthy microbiota is the first line of defense against infections. Probiotics increase the activity of NK (Natural Killer) cells, stimulate antibody production, and reduce inflammation markers — thereby decreasing the risk of chronic diseases.
Via the gut-brain axis, probiotics positively influence the production of serotonin and GABA. Clinical studies show a measurable reduction in anxiety and low mood after 4 to 8 weeks of supplementation with specific strains.
Certain strains (notably Bifidobacterium lactis and Lactobacillus plantarum) are clinically associated with a reduction in fat accumulation, improved insulin sensitivity, and appetite regulation via GLP-1 and PYY hormones.
Specific Lactobacillus strains inhibit the proliferation of pathogenic bacteria responsible for cavities and gingivitis. Oral health is closely linked to the overall state of the gut microbiota.
Acne, eczema, psoriasis, and rosacea are all skin conditions linked to imbalances in the gut microbiota. Preliminary studies show that restoring gut flora improves skin condition by reducing systemic inflammation.
A meta-analysis published in Nutrients (2020) covering 82 randomized controlled trials concludes that multi-strain probiotics show significantly superior effects to single strains for digestive and immune health. Researchers emphasize the critical importance of the viability of strains upon arrival in the intestine — a factor often overlooked by standard capsule formulas.
Vaginal flora is a bacterial ecosystem distinct from the gut microbiota, but closely influenced by it. Under normal conditions, vaginal flora is 90-95% dominated by Lactobacilli — mainly Lactobacillus acidophilus, Lactobacillus crispatus, and Lactobacillus rhamnosus — which maintain an acidic pH (3.8-4.5) protective against infections.
An imbalance in the gut microbiota (dysbiosis) can lead to a change in vaginal flora via the entero-genital pathway. This is why recurrences of bacterial vaginosis, yeast infections, and cystitis are often associated with an impoverished gut microbiota. Conversely, restoring a healthy gut microbiota helps normalize vaginal flora.
Which strains for intimate flora?
The strain Lactobacillus acidophilus — present in our Premium Encapsulated Probiotics formula — is the most studied for its action on vaginal flora. It produces lactic acid and hydrogen peroxide (H₂O₂), two molecules that inhibit the proliferation of pathogenic bacteria such as Gardnerella vaginalis and fungi such as Candida albicans.
A study published in the Journal of Lower Genital Tract Disease (2019) involving 125 women with recurrent bacterial vaginosis shows that oral supplementation with Lactobacillus acidophilus for 6 weeks significantly reduces the recurrence rate (−54% versus placebo) and normalizes vaginal pH in 78% of cases. The authors conclude that the oral route is as effective as the vaginal route for restoring intimate flora via the gut-vaginal axis.
Oral probiotics support intimate flora but do not replace medical treatment in case of proven infection. If you experience symptoms (abnormal discharge, pain, burning), consult your doctor or gynecologist. Probiotics are used for prevention and in conjunction with treatment, not as a sole treatment.
A child's microbiota is still developing until around 3 years of age. The first months of life — mode of delivery, breastfeeding or formula feeding, introduction of solid foods — largely determine the composition of this microbiota for decades to come. A diversified microbiota from childhood is associated with better immune development, a reduced risk of allergies, and better mental health.
From what age?
Our Premium Encapsulated Probiotics is formulated and clinically tested for children aged 3 and over. The dose is the same as for adults (15 ml per day), and the liquid format with natural lemon flavor makes it easier for children to take, as they are much more accepting of a small amount of fruity liquid than a capsule.
When are probiotics particularly useful for children?
Situations where probiotic supplementation is particularly recommended for children include antibiotic use (which indiscriminately destroys good and bad bacteria), infectious diarrhea, recurrent ENT infections (nasopharyngitis, otitis), allergies and atopic eczema, and functional intestinal disorders (colic, constipation, bloated stomach).
A meta-analysis published in the Cochrane Database of Systematic Reviews (2019) analyzing 33 clinical trials involving 6,352 children concluded that probiotics reduce the risk of antibiotic-associated diarrhea in children by 51%. The authors recommend taking them simultaneously with antibiotics (2 hours apart) and for at least 2 weeks after the end of treatment. The strains Lactobacillus acidophilus and Bifidobacterium lactis show the most consistent results.
Our Premium Encapsulated Probiotics can be taken neat as a shot or diluted in 200 ml of water, fruit juice or compote. For children on antibiotics, allow a 2-hour interval between the medication and the probiotic to prevent the antibiotic from destroying the probiotic bacteria before they reach the intestine.
Why microencapsulation changes everything
This is the central problem with all traditional capsule probiotics: the vast majority of bacteria die before reaching the intestine. The stomach produces hydrochloric acid with a pH of 1.5 to 3.5 — an extremely hostile environment that destroys between 60 and 90% of unprotected bacteria in less than 30 minutes.
Added to this is the action of bile salts in the duodenum, which form a second lethal barrier for fragile strains. Result: an ordinary capsule probiotic may claim 10 billion CFUs on the label, but deliver only a few million live ones to your colon — 100 to 1,000 times less than the advertised dose.
How does microencapsulation work?
The patented microencapsulation technology used in our formula envelops each bacterium in a protective lipid capsule that resists gastric acidity and bile salts. This envelope dissolves precisely in the small intestine — where the bacteria need to colonize — releasing the live and active strains exactly where they are needed.
In addition to microencapsulation, our strains are Tyndallized — a discontinuous thermal process that ensures their long-term stability without refrigeration before opening, while preserving their biological effectiveness.
Our Formula: Premium Encapsulated Probiotics
Premium Encapsulated Probiotics
500 ml · 15 ml per dose · 33-day supply · 10 billion CFU per dose · 4 microencapsulated strains · Vitamin C 80 mg (100% NRV) · Vegan L-Glutamine 50 mg · 100% natural flavors and colors.
Discover the product →Our concentrated liquid formula contains 4 clinically tested and microencapsulated strains, selected for their complementarity and documented efficacy on the main desired benefits:
| Strain | Clinically documented benefits |
|---|---|
| Bifidobacterium lactis | Constipation, transit, immunity (NK cells, antibodies), cholesterol reduction, inflammation |
| Lactobacillus acidophilus | Vaginal flora, antibiotic-associated diarrhea, IBS, calcium and lactose absorption |
| Lactobacillus plantarum | Intestinal permeability (leaky gut), inflammation, cardiovascular health, gut-brain axis |
| Lactobacillus salivarius | Oral health, reduction of oral pathogens, atopic eczema, ENT infections in children |
The formula is supplemented with vitamin C (80 mg, 100% NRV) — whose immune benefits are recognized by the EFSA — and vegan L-Glutamine (50 mg), an essential amino acid for intestinal mucosal integrity.
How to take Premium Encapsulated Probiotics?
15 ml every morning — as a pure shot or diluted in 200 ml of water or juice. Shake lightly before use. Store at room temperature before opening, in the refrigerator after. Consume within 2 months after opening. Suitable for adults and children from 3 years of age.
Your microbiota deserves the best bacteria
10 billion microencapsulated probiotics that survive stomach acid and truly colonize your gut. Vegan, sugar-free, from 3 years old.
View Premium Encapsulated Probiotics →FAQ — Frequently Asked Questions about Probiotics
Gynecologist practicing in Paris for 18 years, specialized in women's hormonal health, perimenopause and menopause. At Nutremys LAB, she brings her medical perspective to every product we offer.
Learn more →The information shared on this blog is for educational and informational purposes only. It does not replace medical consultation, diagnosis or treatment prescribed by a healthcare professional. If you have symptoms, are undergoing treatment or are pregnant, consult your doctor before modifying your diet or starting supplementation. Nutremys LAB food supplements should not replace a varied, balanced diet or a healthy lifestyle.
